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2026-07
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DSMZ
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Procell Inc
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Biopharm GmbH
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2026-07
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Egens Biotechnology
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SMAC Corp
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Technical Manufacturing Company
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Allogen Laboratories
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Beijing Xiehe Pharmaceutical Co Ltd
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Shanghai GenePharma
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Chemon Inc
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Image Search Results
Journal: Pharmaceuticals
Article Title: Characterization of a Novel Family of Contilisant + Belinostat Multitarget Small Molecules in Glioblastoma
doi: 10.3390/ph19010020
Figure Lengend Snippet: Novel MTP compounds present antitumor activity. ( A ) IC50 values of MTP142, MTP156 and MTP150 in NHA. ( B ) IC50 values of MTP142, MTP156 and MTP150 in MKN45, RWP1 and H1299 cell lines. ( C ) Quantification of phospho-Histone 3 and cleaved Caspase 3 marker after the administration of increasing concentrations of MTP142, MTP156 and MTP150 in the U87 cell line ( D ) Quantification of phospho-Histone 3 and cleaved Caspase 3 marker after the administration of increasing concentrations of MTP142, MTP156 and MTP150 in GNS166 cells. ( E ) Representative images of p-H3 and Casp3 markers in GNS166 cells. Scale bar of 200 μm. ( F ) Flow cytometry analysis of GNS166 treated with 5 μM MTP156, MTP150 or Belinostat. # p ≤ 0.1, * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001.
Article Snippet:
Techniques: Activity Assay, Marker, Flow Cytometry